Drug Interaction

Drug Interacting Substances

Drug Interacting Substances

  Xenobiotics, whether they are drugs or not, can influence the activity of drug-metabolizing enzymes in a variety of ways.   Inducers: are xenobiotics that cause an increase in the drug-metabolizing activity of a target enzyme, usually by increasing the concentration of the enzyme in the liver or other tissue. Several CYP450 enzymes and glucuronosyltransferases…