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NAPLEX Exam Syllabus

A strong understanding of the NAPLEX syllabus will aid in your preparation to take the examination. The NAPLEX Exam Syllabus is very broad and can divided into several parts as mentioned below:

 

Area 1 – Obtain, Interpret, or Assess Data, Medical, or Patient Information (Approximately 18% of Test)

  • From instruments, screening tools, laboratory, genomic or genetic information, or diagnostic findings
  • From patients: treatment adherence, or medication-taking behavior; chief complaint, medication history, medical history, family history, social history, lifestyle habits, socioeconomic background
  • From practitioners: treatment adherence, or medication-taking behavior; chief complaint, medication history, medical history, family history, social history, lifestyle habits, socioeconomic background
  • From medical records: treatment adherence, or medication-taking behavior; chief complaint, medication history, medical history, family history, social history, lifestyle habits, socioeconomic background
  • Signs or symptoms of medical conditions, healthy physiology, etiology of diseases, or pathophysiology
  • Risk factors or maintenance of health and wellness
  • Evidence-based literature or studies using primary, secondary, and tertiary references

 

Area 2 – Identify Drug Characteristics (Approximately 14% of Test)

  • Pharmacology, mechanism of action, or therapeutic class
  • Commercial availability; prescription or non-prescription status; brand, generic, or biosimilar names; physical descriptions; or how supplied
  • Boxed warnings or REMS
  • Pregnancy or lactation

 

Area 3 – Develop or Manage Treatment Plans (Approximately 35% of Test)

  • Triage or medical referral
  • Therapeutic goals or outcomes and clinical endpoints
  • Medication reconciliation; indication or therapeutic uses; lack of indication; inappropriate indication; duplication of therapy; omissions
  • Drug dosing or dosing adjustments; duration of therapy
  • Drug route of administration, dosage forms, or delivery systems
  • Drug contraindications, allergies, or precautions
  • Adverse drug effects, toxicology, or overdose
  • Drug interactions
  • Therapeutic monitoring parameters, monitoring techniques, monitoring tools, or monitoring frequency
  • Drug pharmacokinetics or pharmacodynamics
  • Evidence-based practice
  • Non-drug therapy: lifestyle, self-care, first-aid, complementary and alternative medicine, or medical equipment

 

Area 4 – Perform Calculations (Approximately 14% of Test)

  • Patient parameters or laboratory measures
  • Quantities of drugs to be dispensed or administered
  • Rates of administration
  • Dose conversions
  • Drug concentrations, ratio strengths, osmolarity, osmolality, or extent of ionization
  • Quantities of drugs or ingredients to be compounded
  • Nutritional needs and the content of nutrient sources
  • Biostatistics, epidemiological, or pharmacoeconomic measures
  • Pharmacokinetic parameters

 

Area 5 – Compound, Dispense, or Administer Drugs, or Manage Delivery Systems (Approximately 11% of Test)

  • Physicochemical properties of drug products affecting compatibility, stability, delivery, absorption, onset, duration, distribution, metabolism, or elimination
  • Techniques, procedures, or equipment for hazardous or non-hazardous sterile products
  • Techniques, procedures, or equipment for hazardous or non-hazardous non-sterile products
  • Equipment or delivery systems
  • Instructions or techniques for drug administration
  • Packaging, storage, handling, or disposal

 

Area 6 – Develop or Manage Practice or Medication-Use Systems to Ensure Safety and Quality (Approximately 7% of Test)

  • Interdisciplinary practice, collaborative practice, or expanded practice responsibilities
  • Continuity of care or transitions of care
  • Disease prevention or screening programs; or stewardship
  • Vulnerable populations, special populations, or risk prevention programs
  • Pharmacy informatics

 

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